Immuno- and Gene Therapy of Neuroectodermal and Hematopoetic Neoplasia (Project H)

Author: Dr. med. Ralf Herold, Last modification: 2004/06/16

Immuno- and Gene Therapy of Neuroectodermal and Hematopoetic Neoplasia

Immuno- and gene therapeutic approaches (immuno- and pharmacogenetic therapy, oncogen repression, transplantation of haploid stem cells) seem especially useful in cases of pediatric malignomas characterized by only a few specific genetic aberrations. The long term goal is to improve the quality of prognosis by developing tests for selected oncologic diseases that are presently uncurable with conventional therapy. We have therefore combined several experimental, pharmaceutical, and clinical immuno- and gene therapeutical approaches to therapy of neuroectodermal and hematopoetic neoplasia within the Competence Network on Pediatric Oncology and Hematology and brought togehter six centers of excellence on this field.