Malignant diseases of the bone marrow
Accounting for 34% of all childhood cancers and showing an incidence of about 600 newly diagnosed young patients in Germany per year, leukaemias are the most frequent malignancies in German children and teenagers. Leukaemias originate in the bone marrow, where the blood is produced. Typical for leukaemias is unlimited proliferation of immature (dysfunctional) white blood cells. There are lymphoblastic and myeloid leukaemias, the courses of which can be either acute or chronic. In childhood and adolescence, most (about 95% of) leukaemias are acute. This means that they are usually progressing fast.

Acute lymphoblastic leukaemia
Accounting for 80 % of all childhood leukaemias, ALL is the most frequent blood cancer in children and teenagers. Here you will find our information on this disease and the corresponding current treatment concepts.

• » Summary

Acute myeloid leukaemia
About 15 % to 20 % of leukaemias in children and teenagers are AMLs. Here, you will find our information on this disease as well as the corresponding current treatment concepts.

• » Summary

Almost all European
children and teenagers with leukaemia are treated according to standardised, continuously optimised protocols based on clinical trials. Currently active trials:

AIEOP-BFM ALL 2009 AIEOP-BFM ALL 2009 COALL 08-09 EsPhALL INTERFANT 06 B-NHL BFM 04 ALL-REZ BFM 2002 ALL-SZT 2003 AML-BFM 2004 AML Relapsed 2009 AML SCT-​BFM 2007 CML-paed II

Treatment guidelines, follow-up plans, reports on clinical trials and additional related information:

ALL / AML guidelines ALL / AML guidelines Guidelines for aftercare Literature on clinical trials Follow-up plans Checklists OncoWorkStation

you will find a selection of additional information on leukaemias provided by external sources here:

Competence Net Leukaemias Competence Net Leukaemias Nat. Cancer Inst. / ALL Nat. Cancer Inst. / AML National Cancer Institute / MDS German Childhood Cancer Foundation Cancer Information Service (Krebsinformationsdie...